Table 1.
Plasma Levels of TSP1 and Cytokines in Patients with RA
| Protein/Cytokine | Control (N=13) | RA (N=20) | Significance | ||
|---|---|---|---|---|---|
| Mean | SEM | Mean | SEM | (P) | |
| Coagulation related protein | |||||
| TSP1 | 25.45 | 7.36 | 315.04 | 86.69 | 0.001 |
| Cytokine | |||||
| IL1β | 4.17 | 3.17 | 25.78 | 11.16 | NS |
| IL4 | 150.84 | 71.73 | 1810.9 | 508.78 | 0.001 |
| IL5 | 416.89 | 183.13 | 2338.8 | 503.59 | 0.025 |
| IL6 | 24.37 | 17.94 | 182.78 | 50.23 | 0.005 |
| IL12 | 38.33 | 22.33 | 609.38 | 135.51 | 0.002 |
| IL12B | 581.37 | 343.73 | 3356.34 | 875.39 | 0.039 |
| IL13 | 41092.89 | 9557.77 | 61110.87 | 13404.17 | NS |
| TNFα | 155.47 | 71.14 | 452.46 | 134.72 | 0.067 |
| IFNγ | 2784.28 | 1204.62 | 21440.27 | 8525.82 | 0.032 |
| TGFβ | 4571.01 | 634.58 | 10139.83 | 2072.27 | 0.1 |
| Chemokine | |||||
| IL8 | 3501.98 | 553.05 | 4378.39 | 511.25 | NS |
| CCL4/MIP1β | 77.74 | 29.90 | 219.33 | 29.65 | 0.014 |
| CXCL10/IP10 | 2571.27 | 914.68 | 12765.00 | 2305.93 | 0.001 |
Italicized value represents statistical trends (when p value is between 0.1 and 0.05)