Table 1.
Demographics of children with JDM in expression profiling study.
Patient No. | Age at Onset | DAS Skin | DAS Weak | DAS Total | Age at MBx | Duration of Untreated Disease (Months) | DQA 0301 | DQA 0501 | TNF Type |
Short Disease Duration | |||||||||
1 | 4.7 | 4.0 | 7.0 | 11.0 | 4.8 | 1.1 | neg | pos | GA |
2 | 6.8 | 7.0 | 9.0 | 16.0 | 6.8 | 1.1 | neg | pos | GG |
3 | 5.5 | 4.0 | 4.0 | 8.0 | 5.50 | 0.6 | neg | pos | GA |
Mean | 5.6 | 5.0 | 6.7 | 11.7 | 5.7 | 0.9 | |||
ST. Dev. | 1.0 | 1.7 | 2.5 | 4.0 | 1.1 | 0.3 | |||
Long Disease Duration | |||||||||
4 | 1.0 | 6.0 | 5.5 | 11.5 | 3.5 | 30.6 | neg | pos | GA |
5 | 1.8 | 6.0 | 3.0 | 9.0 | 2.3 | 6.1 | pos | neg | GG |
6 | 8.3 | 9.0 | 10.0 | 19.0 | 8.5 | 2.1 | neg | neg | GG |
7 | 8.8 | 5.0 | 4.0 | 9.0 | 9.0 | 2.6 | neg | pos | GA |
8 | 3.9 | 6.0 | 9.0 | 15.0 | 5.2 | 16.1 | neg | neg | GG |
9 | 1.6 | 7.0 | 9.0 | 16.0 | 2.2 | 7.7 | pos | neg | GG |
10 | 7.2 | 8.0 | 6.0 | 14.0 | 7.4 | 2.2 | pos | neg | GG |
11 | 8.3 | 4.0 | 8.0 | 12.0 | 8.7 | 4.9 | neg | pos | AA |
12 | 6.0 | 7.0 | 3.0 | 10.0 | 7.7 | 20.6 | pos | pos | GG |
13 | 7.7 | 6.0 | 7.0 | 13.0 | 8.2 | 6.4 | neg | pos | GG |
14 | 2.5 | 3.0 | 1.0 | 4.0 | 3.6 | 13.6 | neg | neg | GG |
15 | 2.6 | 7.0 | 3.0 | 10.0 | 11.3 | 105.6 | neg | neg | GA |
16 | 6.1 | 7.0 | 10.0 | 17.0 | 6.6 | 6.6 | neg | neg | GA |
17 | 4.5 | 6.0 | 6.0 | 12.0 | 5.2 | 8.5 | neg | pos | GG |
18 | 5.1 | 6.0 | 8.0 | 14.0 | 10.3 | 63.5 | neg | pos | AA |
19 | 8.4 | 6.0 | 1.0 | 7.0 | 8.6 | 3.2 | neg | pos | GG |
Mean | 5.1 | 6.2 | 5.8 | 12.0 | 6.7 | 18.8 | |||
ST. Dev. | 2.8 | 1.4 | 3.1 | 3.9 | 2.9 | 27.9 |
DAS: disease activity score; MBx: muscle biopsy; DQA: Major histocompatibility complex, class II, DQ alpha-1; TNF type: Tumor necrosis factor -308 allele.