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. 1999 May;10(5):1409–1427. doi: 10.1091/mbc.10.5.1409

Figure 7.

Figure 7

Ionomycin stimulates apical transport of pIgR–dIgA complexes even in the absence of dIgA-induced PTK stimulation. MDCK cells expressing pIgR-WT (A) or pIgR-725t (B) were submitted to the simplified postmicrotubule-dependent assay. Where indicated the cells were exposed basolaterally to dIgA at stage B, to ionomycin (1 μM) at stage C, and/or to PP1 (10 mM) 1 h before and throughout the assay. n = 4; at least p < 0.005 for dIgA, +dIgA + Iono, and dIgA + iono + PP1 in A and +dIgA + Iono in B; at least p > 0.5 for Iono and dIgA + PP1 in A and for Iono and dIgA in B.