Table 1.
Alignment statistics of the homologous Transcription initiation factor IIA (TFIIA) gamma chain sequences from Plasmodium falciparum and Arabidopsis thaliana.
| Alignment method | Blastp | Smith-Waterman | |
| Substitution matrix | BLOSUM62 | BLOSUM62 | DirAtPf100 |
| Statistics | |||
| P-value (Karlin-Altschul) | 0.008 | NA | NA |
| Z-value (Pearson-Lipman) | 10 | 11 | 12 |
| T-value (TULIP theorem) | 0.01 | 8.10-3 | 7.10-3 |
| P-value (this work) | 1.5.10-6 | 3.7.10-7 | 1.10-7 |
TFIIA gamma sequences from Plasmodium (UniProtKB Q8I4S7_PLAF7) and Arabidopsis (UniProtKB T2AG_ARATH) were aligned with Blastp and Smith-Waterman methods. Statistics were computed following the Karlin-Altschul model (as implemented in the Blastp algorithm) or the Lipman-Pearson Z-value model. The upper bound for the P-value based on the TULIP theorem is given following the formula: T-value = 1/Z-value2. The P-value deduced from the Z-value Gumbel distribution was computed following the model presented here. Substitution matrices were either BLOSUM62, or the asymmetric DirAtPf100 matrix specified for Plasmodium vs. Arabidopsis comparisons. NA: not applicable.