Table 1. Iris grade and ocular associated findings in 30 Mexican nonrelated aniridia cases.
| Case | Sex | Age (years) | Inheritance | Iris grade | Best corrected visual acuity | Nystagmus | Cataract | Glaucoma/ treatment | Macular hypoplasia | Other |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
F |
4 |
Sporadic |
Iris 5 |
20/600 |
+ |
- |
- |
- |
- |
| 2 |
M |
18 |
Familial |
Iris 4 |
20/200 |
+ |
+ |
- |
+ |
Ptosis |
| 3 |
F |
11 |
Sporadic |
Iris 6 |
20/100 |
- |
+ |
- |
- |
Ptosis |
| 4 |
M |
0.5 |
Sporadic |
Iris 5 |
FF |
+ |
- |
- |
+ |
- |
| 5 |
F |
3 |
Sporadic |
Iris 5 |
20/380 |
+ |
- |
- |
+ |
Ptosis, strabismus |
| 6 |
F |
15 |
Familial |
Iris 3 and 4 |
20/25 |
- |
+ |
- |
- |
- |
| 7 |
M |
33 |
Familial |
Iris 5 |
FC 0.5 mt |
+ |
+ |
+, SG, MD |
+ |
Kerathopathy |
| 8 |
F |
3 |
Sporadic |
Iris 6 |
FF |
+ |
- |
- |
+ |
- |
| 9 |
F |
9 |
Sporadic |
Iris 5 |
20/200 |
+ |
+ |
- |
+ |
Ptosis |
| 10 |
F |
6 |
Sporadic |
Iris 5 |
20/40 |
+ |
- |
- |
+ |
- |
| 11 |
M |
10 |
Familial |
Iris 6 |
FC 4 mt |
+ |
+ |
+, SG, MD |
+ |
Ectopia lentis, ONH |
| 12 |
M |
8 |
Sporadic |
Iris 5 |
FC 1 mt |
+ |
- |
congenital, SG, MD |
+ |
Corneal leucoma |
| 13 |
F |
0.8 |
Sporadic |
Iris 5 |
FF |
- |
- |
- |
- |
- |
| 14 |
M |
14 |
Sporadic |
Iris 5 |
20/40 |
- |
+ |
- |
- |
- |
| 15 |
F |
47 |
Sporadic |
Iris 6 |
FC 1.5 mt |
+ |
+ |
+, SG, MD |
+ |
Kerathopathy, ONH |
| 16 |
F |
0.5 |
Sporadic |
Iris 5 |
FF |
- |
+ |
- |
- |
- |
| 17 |
F |
2 |
Sporadic |
Iris 5 |
FF |
- |
- |
+, MD |
+ |
Ectopia lentis, microcornea |
| 18 |
F |
0.5 |
Sporadic |
Iris 5 |
FF |
+ |
- |
- |
+ |
Ectopia lentis, microcornea, ONH |
| 19 |
M |
16 |
Sporadic |
Iris 6 |
20/200 |
+ |
+ |
- |
- |
Ptosis, strabismus |
| 20 |
? |
? |
? |
? |
? |
? |
? |
? |
? |
? |
| 21 |
M |
1 |
Familial |
Iris 5 |
FF |
+ |
- |
- |
+ |
- |
| 22 |
F |
8 |
Familial |
Iris 6 |
20/130 |
+ |
+ |
- |
- |
- |
| 23 |
M |
16 |
Sporadic |
Iris 5 |
20/160 |
+ |
+ |
- |
+ |
- |
| 24 |
M |
5 |
Sporadic |
? |
? |
? |
? |
? |
? |
? |
| 25 |
F |
13 |
Familial |
Iris 5 |
20/200 |
+ |
+ |
- |
+ |
Ectopia lentis |
| 26 |
F |
17 |
Sporadic |
Iris 6 |
20/200 |
+ |
+ |
- |
- |
Strabismus |
| 27 |
F |
0.7 |
Familial |
Iris 6 |
FF |
- |
+ |
congenital, SG, MD |
? |
Corneal leucoma |
| 28 |
F |
1 |
Familial |
Iris 5 |
FF |
+ |
- |
- |
+ |
- |
| 29 |
F |
6 |
Familial |
Iris 5 |
20/120 |
+ |
- |
- |
- |
- |
| 30 | M | 0.4 | Familial | Iris 6 | FF | + | - | - | - | - |
M: Male; F: Female; Iris 3: circumpupillary iris hypoplasia; Iris 4: atypical sector coloboma; Iris 5: subtotal aniridia; Iris 6: complete aniridia; FF: fix and follow; FC: finger count; +: present; -: absent; ?: information not available; SG: surgical; MD: medical; ONH: optic nerve hypoplasia.