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. 2008 Jul 9;9(7):R111. doi: 10.1186/gb-2008-9-7-r111

Table 1.

Common genes significantly decreased in glaucomatous ONH astrocytes compared to their normal counterparts

AAG-AA (U133Av2) CAG-CA (U95Av2)


Symbol Description CL FC p-value FC p-value
AMIGO2 Adhesion molecule with Ig-like domain 2 12q13.11 -1.52 0.0498 -2.01 0.0011
BMP1 Bone morphogenetic protein 1 8p21 -1.92 0.0005 -2.08 0.0001
CD97 CD97 molecule 19p13 -1.65 0.0015 -1.36 0.0008
CRIP2 Cysteine-rich protein 2 14q32.3 -2.58 0 -1.44 0.0034
DGKA Diacylglycerol kinase, alpha 80 kDa 12q13.3 -1.54 0.0034 -1.28 0.0001
DMPK Dystrophia myotonica-protein kinase 19q13.3 -2.45 0 -1.62 0.0021
EFHD1 EF-hand domain family, member D1 2q37.1 -4 0 -2.01 0.0011
GPC1 glypican 1 2q35-q37 -1.61 0.0032 -1.31 0.0026
MGLL Monoglyceride lipase 3q21.3 -1.52 0.0083 -1.75 0.0005
MICAL2 Microtubule associated monoxygenase, calponin and LIM domain containing 2 11p15.3 -1.62 0.0186 -2.02 0.0013
NPAL3 NIPA-like domain containing 3 1p36.12-p35.1 -1.54 0.0034 -1.51 0.0079
PDGFA Platelet-derived growth factor alpha polypeptide 7p22 -1.65 0.0076 -2.21 0.0004
SLC12A2 Solute carrier family 12, member 2 5q23.3 -1.61 0.0032 -1.51 0.0001
SLC12A4 Solute carrier family 12, member 4 16q22.1 -2.42 0.0007 -1.19 0.0046
SMTN Smoothelin 22q12.2 -1.79 0.0162 -1.99 0.001
WWP2 WW domain containing E3 ubiquitin protein ligase 2 16q22.1 -1.87 0.0006 -1.39 0.0029

CL, chromosome location; FC, fold change.