Table 5.
Putative response elements and their locations in the CYP19A1 and CYP19A2 promoter regions.
| Gene | Response Element | Location |
|---|---|---|
| CYP19A1 | GATA-1 | −396 to −384 |
| GATA-1 | −373 to −361 | |
| NF-kappaB | −360 to −349 | |
| PPAR | −312 to −290 | |
| AHR | −264 to −240 | |
| ER | −221 to −203 | |
| SF1/Ad4BP | −188 to −181 | |
| CRE | −124 to −104 | |
| TATA box | −100 to −84 | |
| CYP19A2 | GATA-3 | −1213 to −1201 |
| AR | −1063 to −1045 | |
| CAR/RXR | −773 to −763 | |
| AR | −705 to −688 | |
| NF-kappaB | −522 to −510 | |
| ERE/ER | −498 to −480 | |
| AHR/ARNT | −419 to −413 | |
| PR | −324 to −306 | |
| SF1/Ad4BP | −182 to −177 | |
| TATA box | −176 to −160 | |
Locations numbered back from atg (+1) start site. GenBank Accession nos. EU045309 and EU045310, respectively. PCR primer locations, putative response elements and transcription initiation sites are depicted in supplemental figure.