Table 5.
Putative response elements and their locations in the CYP19A1 and CYP19A2 promoter regions.
Gene | Response Element | Location |
---|---|---|
CYP19A1 | GATA-1 | −396 to −384 |
GATA-1 | −373 to −361 | |
NF-kappaB | −360 to −349 | |
PPAR | −312 to −290 | |
AHR | −264 to −240 | |
ER | −221 to −203 | |
SF1/Ad4BP | −188 to −181 | |
CRE | −124 to −104 | |
TATA box | −100 to −84 | |
CYP19A2 | GATA-3 | −1213 to −1201 |
AR | −1063 to −1045 | |
CAR/RXR | −773 to −763 | |
AR | −705 to −688 | |
NF-kappaB | −522 to −510 | |
ERE/ER | −498 to −480 | |
AHR/ARNT | −419 to −413 | |
PR | −324 to −306 | |
SF1/Ad4BP | −182 to −177 | |
TATA box | −176 to −160 |
Locations numbered back from atg (+1) start site. GenBank Accession nos. EU045309 and EU045310, respectively. PCR primer locations, putative response elements and transcription initiation sites are depicted in supplemental figure.