Table 2.
Summary of the immunofluorescence patterns of cell transfection studies
| Construct | Association with MLS/myofibrils
|
Disruption of MLS/myofibrils
|
Nulcear localization
|
|||
|---|---|---|---|---|---|---|
| BHK-21/C13 | C2C12 | BHK-21/C13 | C2C12 | BHK-21/C13 | C2C12 | |
| Mp2 | − | − | − | − | − | − |
| Mp3 | − | − | − | − | − | − |
| Mp2–Mp3 | + | + | + | − | − | − |
| Mp1–Mp3 | − | + | − | − | + | + |
| Mp4–Mp8 | − | − | − | − | − | − |
| Mp9–Mp13 | − | + | − | − | − | − |
a
BHK-21/C13 cells and C2C12 cells were transiently transfected with the M-protein constructs listed in column 1. Columns 2-7 give the respective localization and/or the effect of each construct as analyzed by immunofluorescence microscopy. For details see RESULTS.