Table 1.
Selected demographics of study subjects.
Low Cotinine | High Cotinine | ||
Number of subjects | 38 | 24 | |
Mean Age ± SD | 47 ± 9 | 46 ± 5 | |
COPD | 2 (5.3%) | 4 (16.7%) | |
Diagnosis of Diabetes (Number (% of total)) | *Any | 13 (34%) | 2 (8.3%) |
Type 1 | 2 (5%) | 1 (4%) | |
Type 2 | 11 (29%) | 1 (4%) | |
CAD Family History | 20 (53%) | 15 (63%) | |
Hyperlipidemia | 24 (63%) | 16 (67%) | |
Automated Differential Blood Count | White Blood Cells (× 109 /L ± SD) | 8.42 ± 2.67 | 9.00 ± 2.41 |
Neutrophils (× 109 /L ± SD) | 5.67 ± 2.18 | 5.76 ± 1.94 | |
Lymphocytes (× 109 /L ± SD) | 1.90 ± 0.68 | 2.31 ± 0.74 | |
Monocytes (× 109 /L ± SD) | 0.42 ± 0.18 | 0.46 ± 0.21 | |
Basophils (× 109 /L ± SD) | 0.06 ± 0.04 | 0.06 ± 0.04 | |
Eosinophils (× 109 /L ± SD) | 0.22 ± 0.18 | 0.26 ± 0.14 | |
Platelets (× 109/L ± SD) | 252.42 ± 73.97 | 250.67 ± 56.06 |
CAD = Coronary Artery Disease, SD = Standard Deviation, L = liter, fL = femtoliter, dL = deciliter, G = gram, pG = picogram, COPD = Chronic Obstructive Pulmonary Disease. For Student's T-test, automated cell counting values were recalculated as values per gram or liter, and log2 normalized prior to determination of p-Value.
* Fisher's Exact Test shows significant differences between low and high cotinine at p = 0.0315 (2-tail)