Table 4.

Hyperclustered TRANSFAC and GO Category Annotations

Cluster	TRANSFAC Annotations
A	V$POU3F2_02
	V$ISRE_01: interferon-stimulated response element
	V$DEAF1_01
	V$E2F1_Q3_01
	V$MAZR_01: MAZ related factor
	V$KROX_Q6
	V$E2F1DP1_01: E2F-1:DP-1 heterodimer
	V$HNF1_Q6
	V$E2F_Q3_01
	V$E2F1_Q6: E2F-1
Cluster	Common GO Parent Node	Gene Ontology	GO Level	GO Name
B	signal transduction [4] GO:0007165	GO:0007264	6	small GTPase mediated signal transduction
		GO:0007165	4	signal transduction
		GO:0007242	5	intracellular signaling cascade
C	programmed cell death [5] GO:0012501	GO:0006917	8	induction of apoptosis
		GO:0012502	7	induction of programmed cell death
		GO:0043068	6	positive regulation of programmed cell death
		GO:0043065	7	positive regulation of apoptosis
		GO:0050794	3*	regulation of cellular process
		GO:0016265	3*	death
		GO:0008219	4*	cell death
		GO:0012501	5	programmed cell death
		GO:0006915	6	apoptosis
		GO:0043067	5	regulation of programmed cell death
		GO:0042981	6	regulation of apoptosis
D	response to stress [4] GO:0006950	GO:0006950	4	response to stress
E	macromolecule metabolic process [4] GO:0043170	GO:0006493	9	O-linked glycosylation
		GO:0043170	4	macromolecule metabolism
		GO:0044260	5	cellular macromolecule metabolism
		GO:0019222	4*	regulation of metabolism
F	transcription [6] GO:0006350	GO:0006350	6	transcription
		GO:0045449	6	regulation of transcription
		GO:0019219	5*	regulation of nucleo-base, -side, -tide and nucleic acid metabolism
		GO:0006355	7	regulation of transcription, DNA-dependent
		GO:0006351	7	transcription, DNA-dependent
G	cell cycle process [6] GO:0022402	GO:0000082	7	G1/S transition of mitotic cell cycle
		GO:0000132	11	mitotic spindle orientation
H	mevalonate transport [8] GO:0015728	GO:0015728	8	mevalonate transport

* Node is not a child of the parent node for this group