Figure 2. Time changes in the pneumococcal population in the post-vaccine era: global colonization rate (bold line), colonization with vaccine serotypes (dashed line), non-vaccine serotypes (dotted lines), and dual colonization with vaccine and non-vaccine serotypes (full line), a) with a frequency of vaccine-selected capsular switch ← = 0, b) with a frequency of vaccine-selected capsular switch ← = 10−4/week, and c) with a frequency of vaccine-selected capsular switch ← = 10−3/week.
