Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Representation of the “slip-pop” mechanism for phospholipid flipflop. The inherent wobbling motion of a single-pass, membrane-spanning helical peptide causes local defects in the head-group region of the bilayer, which allows neighboring phospholipids to slip into the hydrophobic center of the membrane and subsequently pop outside.19
