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. Author manuscript; available in PMC: 2008 Sep 8.
Published in final edited form as: Cancer Cell. 2006 Aug;10(2):159–170. doi: 10.1016/j.ccr.2006.07.003

Figure 1. Akt activation in tumor vessels.

Figure 1

A–D: VEGF-A-expressing rat C6 glioma cells grown subcutaneously in Nu/Nu mice were double stained with TRITC-lectin (A, red) to label blood vessels and anti-phosphorylated Akt antibody (B, green). Merged images are shown in C, with arrows indicating endothelial cell nuclei positive for phosphorylated Akt. Phosphorylated Akt is also seen in tumor cells. A higher magnification of the blood vessels within the boxed area is shown in D.