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. Author manuscript; available in PMC: 2008 Sep 8.
Published in final edited form as: J Neurophysiol. 2006 Aug 2;96(5):2549–2563. doi: 10.1152/jn.00704.2006

Figure 8.

Figure 8

Effect of Blocking SK or Doubling gAMPA on pattern and rate. A-C. Patterns exhibited at various values of glutamatergic and gabaergic input (parameter space). The dot dashed lines in panels A-C demarcate regions above and to the left that appear to have distinct up and down states. A. Control. B. SK blocked. The regions of single spiking and doublets are nearly eliminated and that for bursting is extended. C. Doubling gAMPA. D. Percent spikes in burst plotted before and after block of SK (green circles) or doubling gAMPA (red crosses). E. Frequency under control conditions. F. Frequency before and after block of SK (green circles) or an increase in the AMPA/NMDA ratio (red crosses).