Figure 5.

Kinetics of FITC-dextran uptake from the basal side of MDCK cells. The middle and basal planes of control and JAS-treated MDCK cells were examined by confocal microscopy after uptake of FITC-dextran for 7.5, 15, and 30 min. JAS-pretreated induced an increase in the number and size of labeled compartments at the basal region at all times (d, h, and l) compared with control cells (c, j, and k). JAS also produced an increase in labeled compartments in the middle region of the monolayer at the later times of 15 (f) and 30 min (j), when compared with control cells after the same uptake times (e and i). Bar, 10 μm.