Table 1.

Micro-CALI of radixin causes lamellipodial retraction half-growth cone studies

Treatment	% Change of lamellipodial surface area over time ± SEM
	Prelaser		During laser		Postlaser
	Unirradiated half	Irradiated half	Unirradiated half	Irradiated half	Unirradiated half	Irradiated half
MG-IgG loaded cells (n = 22)	0.55%  ± 0.65	−0.60%  ± 0.81	0.51%  ± 0.61	0.71%  ± 0.82	1.24%  ± 0.96	−0.33%  ± 0.85
MG-457-3 loaded cells (n = 25)	0.28%  ± 1.12	0.24%  ± 1.21	−1.48%  ± 1.72	−30.48%  ± 2.47a	0.39%  ± 1.20	2.14%  ± 1.01

Percent change of lamellipodial surface area was measured for irradiated and nonirradiated halves of MG IgG (control) and MG 457-3 growth cones over 5 min. As lamellipodia extend and retract over time, the average percent change for untreated growth cones is close to 0% (0.35% ± 0.74, n = 11). Significance was measured by Student’s two-tailed, paired, t test. 

^ap < 0.0001.