Table 2.
Micro-CALI of radixin causes growth cone splitting
| Treatment | % Of growth cones that split |
|---|---|
| MG-457-3 (n = 25) | 84a |
| MG-220 (n = 23) | 87a |
| MG-IgG (n = 22) | 5 |
| 457-3 (no MG) (n = 20) | 0 |
| 220 (no MG) (n = 20) | 0 |
| Untreated (n = 11) | 0 |
Micro-CALI of radixin using MG-457-3 or MG-220 causes growth cone splitting. Splitting is defined as the retraction of lamellipodia of the central region of the growth cone followed by the formation of two distinct growth cones.
a
Significance was determined by the Poisson test, p < 0.0001.