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. Author manuscript; available in PMC: 2008 Dec 18.
Published in final edited form as: Biochemistry. 2007 Nov 17;46(50):14450–14460. doi: 10.1021/bi701310x

Fig 5. Alignment of amino acid sequences of the catalytic domains of FXI and PK.

Fig 5

Shown is an alignment of the primary amino acid sequence of FXI and PK. The diamonds show the amino acids that are different. Based upon this alignment, synthetic peptides (labeled R1–R7) have been designed for the use in competition binding experiments to localize the region of FXIa light chain that mediates binding to the activated platelet surface.