Fig. 6.

Time course of PGE₂ synthesis in RAW 264.7 cells infected with T. gondii via ELISA. The RAW 264.7 cells were infected with T. gondii (▫) or LPS (▪) for 0, 6, 18, 24, and 48 hr, and the supernatant was used (A). The effects of MAPK inhibitors in RAW 264.7 cells infected with T. gondii (B). The RAW 264.7 cells were pretreated with 50 µM NS-398, 20 µM PD98059, 10 µM SB203580, or 10 µM SP600125 for 20 min, and were infected with T. gondii for 48 hr. Data are expressed as the mean ± SD of 3 separate experiments. None; RAW 264.7 cells, T. gondii; T. gondii infection. ^*P < 0.05.