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. 2008 Sep 8;105(39):15172–15177. doi: 10.1073/pnas.0806717105

Fig. 3.

Fig. 3.

Loss of rhythmic expression of clock-regulated metabolic genes in the livers of L-Bmal1−/− mice. (A) One-day temporal expression profiles of selected hepatic metabolic genes. Shown are the mean and SEM of Q-PCR triplicate assays (most error bars are too small to be seen at this scale). G6pt1, glucose-6-phosphate translocase 1; Gck, glucokinase; L-PK, liver pyruvate kinase; Pepck1, phosphoenolpyruvate carboxykinase 1; Pepck2, phosphoenolpyruvate carboxykinase 2; Cpt1, carnitine palmitoyltransferase 1; Ucp2, uncoupling protein 2; AK4, adenylate kinase 4; POR, P450 oxidoreductase. (B) One-day temporal expression profile of hepatic Glut2 (glucose transporter 2) transcript in the indicated genotypes. Shown are mean and SEM of Q-PCR triplicate assays (most error bars are too small to be seen at this scale). (C) One-day expression profile of GLUT2 protein. Shown is a Western blot of liver protein extracts obtained from mice of the indicated genotypes. CT, circadian time.