Unadjusted mean (± 2SE) lower-leg peripheral quantitative computerized tomography (pQCT) skeletal muscle composition measures across 10-y age groups (the numerical values are shown in white boxes inside the bars). n = 214, 444, 348, and 243 for the 40–49, 50–59, 60–69, and ≥70 y age groups, respectively. ANCOVA was used to assess age group differences in pQCT measures after adjustment for height (total adipose tissue and total muscle area) or height, total adipose tissue, and total muscle area (intermuscular and subcutaneous adipose tissue). Differences were significant (P < 0.0001) across age groups for all pQCT measures except total adipose tissue.