TABLE 1.
Projected volume infused using standard concentrations compared with volume actually received using variable concentrations in infants weighing less than 20 kg
| Drug | n | Mean difference in volume (hypothetical – received), mL/kg/day (range) | % difference in volume (hypothetical – received) (95% CI [range]) |
|---|---|---|---|
| Total | 78 | –0.4 (−8.7 to 6.4) | –8.9 (−17 to 0.8) |
| Dopamine | 13 | –0.3 (−1.0 to 0.05) | –20.1 (−32.7 to −7.4) |
| Adrenaline | 7 | –1.6 (−8.7 to 0.06) | –8.7 (−35.9 to 18.5) |
| Fentanyl | 12 | –0.5 (−7.4 to 1.9) | 4.2 (−17.1 to 25.4) |
| Milrinone | 13 | –1.0 (−3.9 to 0.01) | –23.1 (−33.3 to −12.9) |
| Morphine | 30 | 0.2 (−6.0 to 6.4) | –1.2 (−18.8 to 16.4) |
| Vasopressin | 3 | –2.5 (−4.5 to −0.2) | –28 (−54.2 to −2.5) |
n Number of infusions