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. 2008 Sep 12;283(37):25533–25543. doi: 10.1074/jbc.M709962200

FIGURE 4.

FIGURE 4.

MAGP-1 deficiency leads to increased body size and fat deposition. A, side-by-side comparison of representative wild-type (left) and MAGP-1-/- (right) mixed strain mice demonstrates that MAGP-1-/- mice are larger than age-matched wild-types. B, graph showing that BSw MAGP-1-/- male mice have significantly higher body weight at 3 months of age than age-matched BSw wild-type animals. *, p < 0.01 for wild-type versus MAGP-1-/-; error bars indicate mean ± S.E. (n = 34). C, BSw MAGP-1-/- mice have increased fat deposition relative to wild-types. Epididymal fat pads were harvested from 3- and 6-month-old BSw male mice. Fat pad ratio was calculated as fat pad weight (g) divided by body weight (BW, g) and expressed as a percentage. * and ** indicate p < 0.02 and p < 1 × 10-6, respectively, for wild-type versus MAGP-1-/-; error bars indicate mean ± S.E. (n = 38).