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. Author manuscript; available in PMC: 2008 Sep 18.
Published in final edited form as: Adv Exp Med Biol. 2008;617:41–56. doi: 10.1007/978-0-387-69080-3_4

Figure 3. An overview of relationship between mitotic kinase expression and cancer.

Figure 3

As mitosis regulators, the expression levels of the major mitotic kinases are crucial for cell division. In many cancers, up and down regulation of their expression have been observed, underlying the importance to follow the expression level of mitotic kinases for developing new targeted therapy.