Table 3. Antibiotic susceptibilities of the most common organisms isolated from blood cultures of children with serious bacterial infections, according to time of isolation.
| % susceptible | ||||||||||||
| S. pneumoniae | S. aureus | H. influenzae | E. coli | Non-typhoid salmonella | K. pneumoniae | |||||||
| Time ( Total n) | ≤48 hrs (14) | >48 hrs (2) | ≤48 hrs (3) | >48 hrs (9) | ≤48 hrs (3) | >48 hrs (2) | ≤48 hrs (1) | >48 hrs (4) | ≤48 hrs (3) | >48 hrs (6) | ≤48 hrs (0) | >48 hrs (10) |
| Penicillin/Ampicillin | 79a | 50a | 0 | 0 | 100 | 100 | 0 | 50 | 100 | 17 | NA | 0 |
| Amoxicillin +clavulanate | NT | NT | NT | NT | 100 | 100 | 100 | 50 | 100 | 100 | NA | 20b |
| TMP-SMX | NT | NT | 0 | 0 | 67 | 0 | 0 | 75 | 100 | 17 | NA | 0 |
| Cloxacillin/Methicillin | NT | NT | 0 | 0 | NT | NT | NT | NT | NT | NT | NT | NT |
| 3rd generation Cephalosporin | 93c | 100 | NT | NT | 100 | 100 | 100 | 50 | 100 | 20 | NA | 0 |
| Erythromycin | 86 | 50 | 0 | 0 | NT | NT | NT | NT | NT | NT | NT | NT |
| Gentamicin | NT | NT | 0 | 0 | NT | NT | 100 | 50 | NT | NT | NA | 10 |
| Clindamycin | NT | NT | 67 | 33 | NT | NT | NT | NT | NT | NT | NT | NT |
| Ofloxacin/Ciprofloxacin | NT | NT | 33 | 67 | 100 | 100 | 100 | 75 | 100 | 100 | NA | 40 |
| Amikacin | NT | NT | 100 | 78 | NT | NT | 100 | 100 | NT | NT | NA | 90a |
| Pipericillin/Tazobactam | NT | NT | NT | NT | NT | NT | 100 | 75a,c | 100 | 100 | NA | 50a |
| Meropenem | NT | NT | NT | NT | NT | NT | 100 | 100 | 100 | 100 | NA | 100 |
| Vancomycin | NT | NT | 100 | 100 | NT | NT | NT | NT | NT | NT | NT | NT |
a
The remainder were intermediate sensitivity
b
Five isolates intermediate susceptibility
c
One unknown
NT–not tested
NA–not applicable
TMP-SMX–Trimethoprim sulfamethoxazole