Table 4.
All of the SNPs within the 20kb region of IL1A were used to construct haplotypes for the NARAC cases and controls. Haplotypes of a frequency > 0.005 are shown. SNPs are ordered as in Table 1. OR = odds ratio and 95% CI = 95% confidence interval of the OR.
IL1A Haplotype Association with NARAC Cases vs. Controls
| Haplotype | No. | Freq. | OR | 95% CI | P value | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IL1A | cases | ctrls | cases | ctrls | |||||||||||||||
| G | A | C | G | T | G | C | C | C | G | G | C | 776 | 607 | 0.30 | 0.28 | 1.12 | 0.99 | 1.27 | 8.3E-02 |
| T | A | A | G | T | G | A | C | C | A | G | T | 722 | 596 | 0.28 | 0.27 | 1.04 | 0.91 | 1.18 | 5.9E-01 |
| G | G | A | T | C | G | A | T | T | G | G | T | 443 | 443 | 0.17 | 0.20 | 0.82 | 0.70 | 0.94 | 6.0E-03 |
| T | A | A | G | T | G | A | C | C | A | A | C | 319 | 261 | 0.12 | 0.12 | 1.04 | 0.87 | 1.24 | 6.6E-01 |
| T | G | A | T | C | G | A | T | T | G | G | T | 229 | 203 | 0.09 | 0.09 | 0.95 | 0.78 | 1.16 | 6.2E-01 |
| T | A | C | G | T | G | C | C | C | G | G | C | 14 | 26 | 0.01 | 0.01 | 0.45 | 0.24 | 0.87 | 1.5E-02 |
| G | A | A | G | T | G | A | C | C | A | G | T | 10 | 20 | 0.00 | 0.01 | 0.42 | 0.20 | 0.90 | 2.2E-02 |
| Remaining Haplotypes | 83 | 42 | 0.03 | 0.02 | |||||||||||||||