Table 1.

Increase with Biochemotherapy for Cytokine Expressing Cells Defining a Proinflammatory Response with Low Type II Interleukins.

Cytokine Expression	Population Fold-Increase Relative to 100 Cells (95% Confidence Intervals)*
1. CD4+ plus CD8+ cells
IFN-γ†	16.67 (2.938–30.408)
IL-2	3.0 (1.468–4.576)
IL-6†	18.85 (2.418–27.297)
TNF-α	2.49 (1.485–3.498)
IL-4‡	1.21 (0.938–1.473)
IL-13	3.0 (1.866–4.265)
TGF-β	3.56 (1.086–6.049)
IL-10	1.64 (1.007–2.276)
2. F4/80+ cells
IL-12	5.35 (2.898–7.795)
IL-6	6.29 (3.092–9.502)
TNF-α	2.96 (1.764–4.172)

^*Cytokine rates from cells of 11 pairs of treated and control (untreated) animals.

^†Significant differences between IFN-γ and IL-4 and IL-10 (P < .001) or IL-6 and IL-4 and IL-10 (P < .001 and P < .01, respectively).

^‡Only CD4⁺ cells.