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. 2008 Aug 29;105(36):13580–13585. doi: 10.1073/pnas.0804437105

Fig. 1.

Fig. 1.

Abundance of putative BSH and related proteins in the human gut metagenome. Amino acid sequences of putative BSH and related amidases described in Fig. S3, from 15 human gut metagenomes (6, 7), Sargasso sea (24), soil (25), and the combined gut metagenomes of lean and obese mice (8) were used to calculate and compare the relative abundance of these proteins in each metagenome. Abundance was calculated as hits per megabase (Mb) for individual and combined metagenomes and revealed variation between individuals and a general enrichment of BSH and related proteins in the human gut metagenome. Japanese individuals: InA, male 45years; InB, male 6 months; InD, male 35 years; InE, male 3 months; InM, female 4 months; F1-S, T, U, Family I, male 30 years, female 28 years, female 7 months, respectively; F2-V, W, X, Y, Family II, male 37 years, female 36 years, male 3 years, female 1.5 years, respectively. American metagenomes: H 7 & 8, female 28 years combined with male 37 years; HUM COMB, all human metagenomes combined; MUS COMB, all murine metagenomes combined; SARG SEA, Sargasso sea metagenome; SOIL, soil metagenome. Colors indicate putative origin of BSH homologues retrieved from each metagenome or combined metagenomes. Values above bars represent overall hits per Mb for each category.