Fig. 1.

Chronic bryostatin-1 rescued rats' performance in spatial learning and memory but did not affect their sensorimotor ability. (A) Escape latency over training trials (mean ± standard error of the mean). (B–E) Results of the memory retention test after the training trials. Quadrant 4 was the target quadrant where the hidden platform was placed during the training trials. (F) Target quadrant ratio (calculated by dividing the target quadrant swim distance by the average swim distance in the nontarget quadrants). (G) Results in a visible platform test (with a visible platform placed at a new location). Bry, bryostatin-1; Isch, cerebral ischemia; NS, not significant; *, P < 0.05.