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. Author manuscript; available in PMC: 2008 Sep 10.
Published in final edited form as: J Am Chem Soc. 2006 Feb 15;128(6):1840–1846. doi: 10.1021/ja055994d

Table 1.

Relative Reactivity and Selectivity of Asymmetric Ruthenium Catalysts.

graphic file with name nihms63197f8.jpg
11 to 12a 13 to 14a
catalyst eeb(%) convc
(%)		 eeb (%) convc
(%)
2a 35 >98 83 >98
3a 31 >98 81 >98
4a 30 >98 75 >98
5a 46 >98 92 >98
2b 90 >98 86 68
3b 84 >98 90 >98
4b 87 >98 85 >98
5b 90 >98 92 58
a

Reactions with 2a-5a (2 mol %) run in CH2Cl2; catalysts 2b-5b generated by stirring 2a-5a (4 mol %) in THF with 25 equiv NaI.

b

Enantiomeric excesses determined by chiral GC; see supporting information for chromatograms and proof of absolute stereochemistry.

c

Determined by 1H NMR spectrum of crude reaction mixture.