Table 3.
Gene | rs number | Smokers | Non-Smokers | ||||||
Cases/Controls | OR* | 95% CI | p-value | Cases/Controls | OR* | 95% CI | p-value | ||
CD14 | rs2569190 | 77/31 | 2.05 | 1.09–3.87 | 0.027 | 82/121 | 0.93 | 0.62–1.39 | 0.72 |
IL1A | rs17561 | 106/48 | 1.68 | 0.84–3.32 | 0.14 | 111/156 | 1.05 | 0.69–1.60 | 0.83 |
IL1R1 | rs3917318 | 102/45 | 1.138 | 0.67–1.94 | 0.64 | 108/155 | 1.07 | 0.74–1.54 | 0.72 |
IL1B | rs3917365 | 99/44 | 1.63 | 0.78–3.42 | 0.19 | 105/146 | 1.03 | 0.62–1.73 | 0.90 |
IL6 | rs1800797 | 104/43 | 1.28 | 0.66–2.46 | 0.46 | 110/155 | 1.05 | 0.67–1.64 | 0.83 |
rs2069830 | 103/45 | 1.63 | 0.48–5.58 | 0.43 | 109/155 | 0.30 | 0.11–0.82 | 0.019 | |
rs2069832 | 101/45 | 0.69 | 0.35–1.35 | 0.28 | 109/152 | 0.80 | 0.51–1.26 | 0.34 | |
MMP3 | rs679620 | 103/46 | 0.98 | 0.58–1.65 | 0.93 | 110/157 | 1.01 | 0.71–1.43 | 0.97 |
* Adjusted for age and race (African-American, Caucasian, and other).