Table 4.
Thermodynamic descriptions of the bPBPs.1
| LAOBP | HBP | GBP | PhBP | |||
| PDB ID | 1LST | 2LAO* | 1HSL | 1WDN | 1GGG* | 1IXH |
| Tm (K) | 385 | 376 | 336 | 336 | 297 | 386 |
| Cpmax (kcal/mol·K) | 113.6 | 70.8 | 38.5 | 26.4 | 8.7 | 174.1 |
| Barrier (kcal/mol) | 13.6 | 8.4 | 4.3 | 2.6 | 0.0 | 13.1 |
| θnat | 0.8 | 0.9 | 1.0 | 0.8 | n/a2 | 0.9 |
| θTS | 1.2 | 1.3 | 1.3 | 1.1 | n/a | 1.2 |
| θunf | 2.1 | 1.9 | 1.8 | 1.6 | n/a | 2.0 |
1All four bPBP homologs have been crystallized in the ligated conformation. Additionally, two bPBP homologs (marked with asterisks) have been crystallized in the open apo conformation. 2 The apo GBP structure is predicted to have a continuous transition between folded and unfolded.