Table 5. Performance of prediction methods on MHCBN HLA-DRB1*0301 unique, similarity-reduced, and weighted datasets using 5-fold cross-validation test.

Dataset	Method	ACC	Sn	Sp	CC	AUC
UPDS	CTD	72.51	73.95	70.87	0.448	0.787
	LA	71.89	73.56	70.00	0.436	0.795
	5-spectrum	70.26	82.76	56.09	0.405	0.770
SRDS1	CTD	63.41	64.23	62.67	0.269	0.661
	LA	58.54	59.85	57.33	0.172	0.617
	5-spectrum	42.16	63.50	22.67	−0.152	0.323
SRDS2	CTD	59.93	59.06	60.69	0.197	0.628
	LA	55.88	54.33	57.24	0.116	0.563
	5-spectrum	35.29	37.01	33.79	−0.292	0.273
SRDS3	CTD	64.62	60.57	67.91	0.285	0.675
	LA	67.18	61.14	72.09	0.334	0.736
	5-spectrum	63.08	49.71	73.95	0.244	0.678
WUPDS	CTD	65.27	61.04	68.88	0.300	0.678
	LA	66.66	64.47	68.53	0.330	0.710
	5-spectrum	59.97	58.70	61.04	0.197	0.648