TABLE 2.
Cardiac lipid measurement in WT and LpLGPI mice
| WT | WT-myr | LpLGPI | LpLGPI-myr | |
|---|---|---|---|---|
| TG (μg/mg) | 16.8 ± 6.5 | 19.1 ± 9.0 | 18.1 ± 9.5 | 22.2 ± 8.0 |
| Cholesterol (μg/mg) | 4.2 ± 1.0 | 4.2 ± 0.18 | 5.0 ± 1.0 | 5.3 ± 0.7 |
| Fatty acyl CoA (pmol/mg) | 81.4 ± 6.2 | 130.6 ± 4.8a | 41.4 ± 11.2a | 122.1 ± 4.8a,b |
| SM (μg/mg) | 15.2 ± 2.5 | 14.6 ± 2.1 | 22.2 ± 1.9a | 12.2 ± 2.3a,b |
| Ceramide (pmol/mg) | 210.5 ± 11.3 | 216.3 ± 22.6 | 305.9 ± 21.1a | 151.8 ± 9.9a,b |
| DAG (pmol/mg) | 184.4 ± 4.9 | 176.4 ± 8.5 | 233.5 ± 5.6a | 228.0 ± 8.7a |
DAG, diacylglycerol. Results are given as mean ± SEM, n = 8–10.
a
P < 0.05 (vs. WT).
b
P < 0.05 (vs. LpLGPI).