TABLE 3.

Expression of SPT subunits and heart failure markers in WT and LpL^GPI mice

	4 month-old
Gene	WT	WT-myr	LpLGPI	LpLGPI-myr
LCB1	1.00 ± 0.14	2.19 ± 0.19a	0.61 ± 0.05a	1.19 ± 0.19b
LCB2	1.00 ± 0.14	2.32 ± 0.38a	0.87 ± 0.04	1.61 ± 0.22b
ANF	1.00 ± 0.09	0.81 ± 0.22	1.74 ± 0.20a	0.47 ± 0.15a,b
BNP	1.00 ± 0.22	1.14 ± 0.17	2.27 ± 0.45a	0.51 ± 0.12a,b

SPT, serine palmitoyltransferase. Results are given as mean ± SEM, n = 8–10.

^aP < 0.05 (vs. WT).

^bP < 0.05 (vs. LpL^GPI).