TABLE 3.
Chromosomal regions with univariate multipoint LOD scores ⩾ 1.9
| Cytogenetic Position | Closest Marker(s) | Trait | Data Set | LOD Score a (Included Covariates) |
|---|---|---|---|---|
| 4p14-q12 | D4S405-D4S1592 | TC | Samoa | 2.93 (A, A2, S, A2*S) |
| 6p21-p12 | D6S1610-D6S257 | TC | Combined | 2.29 (A, A2, S, A2*S, C, P) |
| D6S1610-D6S257 | TC | Samoa | 2.68 (A, A2, S, A2*S) | |
| D6S1610-D6S257 | LDL | Samoa | 2.67 b (A, A2, A*S, A2*S, D) | |
| D6S1610-D6S257 | LDL | Samoa | 3.13 b (A, A2, S, A*S, A2*S, D, B) | |
| 7q35-q36 | D7S661-D7S636 | TC | American Samoa | 2.27 (A, A2, S, C, P) |
| 9q21 | D9S273-D9S175 | LDL | Samoa | 2.15 b (A, A2, A*S, A2*S, D) |
| D9S273-D9S175 | LDL | Samoa | 2.21 b (A, A2, S, A*S, A2*S, D, B) | |
| 11q23-q24 | D11S925-D11S4151 | LDL | Samoa | 1.96 b (A, A2, A*S, A2*S, D) |
| D11S925-D11S4151 | LDL | Samoa | 2.03 b (A, A2, S, A*S, A2*S, D, B) | |
| 12q21.33-q23.1 | D12S351-D12S346 | TC | American Samoa | 2.26 (A, A2, S, C, P) |
| D12S351-D12S346 | LDL | American Samoa | 3.07 (A, A2, P) | |
| D12S351-D12S346 | TC | Combined | 1.96 (A, A2, S, A2*S, C, P) | |
| 12q23.3 | D12S78 | TC | Combined | 2.05 (A, A2, S, A2*S, C, P) |
| 12q24.23 | D12S86 | TC | Combined | 2.14 (A, A2, S, A2*S, C, P) |
| 12q24.33-qtel | D12S1723-tel | TC | Combined | 2.12 (A, A2, S, A2*S, C, P) |
| D12S1723-tel | LDL | Samoa | 1.96 b (A, A2, S, A*S, A2*S, D, B) | |
| 13q33 | D13S173 | LDL | Combined | 2.25 (A, A2, S, A2*S, D, P) |
| 15q14 | D15S1007-D15S1012 | HDL | Samoa | 1.96 b (S, C, D, B) |
| 16p13 | D16S423-D16S404 | LDL | American Samoa | 2.00 (A, A2, P) |
| 18q23-qtel | D18S70-tel | LDL | American Samoa | 1.91 (A, A2, P) |
| 19p13-q12 | D19S226-D19S414 | LDL | American Samoa | 2.25 (A, A2, P) |
| 19q13 | D19S220 | TC | American Samoa | 1.94 (A, A2, S, C, P) |
| Xq23 | DXS8055 | LDL | Samoa | 2.16 b (A, A2, A*S, A2*S, D) |
| DXS8055 | LDL | Samoa | 2.30 b (A, A2, S, A*S, A2*S, D, B) |
a
Significant covariates (P ≤ 0.1) included in the polygenic model.
b
The corrected LOD score (LODmtc) can be calculated by subtracting 0.3 from the uncorrected LOD score shown. LOD scores ⩾ 3 are highlighted in boldface.