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. 2008 Aug 18;80(1):30–39. doi: 10.1093/cvr/cvn184

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Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that the original authorship is properly and fully attributed; the Journal, Learned Society and Oxford University Press are attributed as the original place of publication with correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org.

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The activity of electron transport chain enzymes in isolated heart subsarcolemmal mitochondria (SSM) and interfibrillar mitochondria (IFM). The enzyme activity was measured in detergent-solubilized, freshly isolated SSM and IFM from control (n = 5) and heart failure (n = 5) dogs, and expressed as nmol/min/mg mitochondrial protein or as the first-order rate constant (k = 1/min/mg mitochondrial protein) for complex IV. NCR, rotenone sensitive NADH-Cytochrome c Reductase; C I, complex I; NFR, NADH-Ferricyanide Reductase; SCR, antimycin A-sensitive Succinate-Cytochrome c Reductase. C II, TTFA-sensitive complex II; C II+Q, TTFA-sensitive Complex II with exogenous coenzyme Q analogue; C III, complex III; C IV, complex IV. Mean ± SEM.