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. Author manuscript; available in PMC: 2008 Sep 11.
Published in final edited form as: J Org Chem. 2006 Jan 20;71(2):629–635. doi: 10.1021/jo052030w

Scheme 4. Synthesis of 1 and 3.

Scheme 4

(a) (i). HC(OMe)3, CSA (cat.), CH2Cl2, rt; ii. DIBAL-H, 0 °C; (b) 15, PPh3, DIAD, THF, 0 °C-rt; (c) CAN, CH3CN/H2O (6:1); (d) i. DGK, [32P]ATP, pH 6.6, 37 °C, 2 h; ii. TMSBr, CH2Cl2, 0 °C.