TABLE 2.
MICs for strains of single-drug-resistant M. tuberculosis
| Compound | MIC (μg/ml)a for:
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| H37Rv | INH-R | RIF-R | TAC-R | EMB-R | CIP-R | KAM-R | ETA-R | PAS-R | |
| 1 | 3.13 | 3.13 | 3.13 | ≤1.56 | ≤1.56 | 3.13 | 3.13 | 3.13 | 3.13 |
| 2 | 3.13 | 6.25 | 3.13 | 1.56 | 25 | 6.25 | 25 | 3.13 | 3.13 |
| 3 | ≤3.13 | 6.25 | ≤3.13 | ≤3.13 | ≤3.13 | 12.5 | ≤3.13 | 6.25 | NDb |
| 4 | 3.13 | ND | 3.13 | 0.39 | ND | 6.25 | ND | 6.25 | 3.13 |
| 5 | 1.56 | 1.56 | 1.56 | ND | 1.56 | 3.13 | 1.56 | ND | ND |
| 6 | 0.2 | 0.39 | 0.2 | ND | 0.2 | 0.2 | ≤0.1 | ND | ND |
| 7 | 0.20 | 0.39 | 0.39 | ND | 0.39 | 0.78 | 0.39 | ND | ND |
| 8 | ≤0.2 | ≤0.2 | ≤0.2 | 0.39 | ND | 0.39 | ND | 0.78 | 0.78 |
| 9 | 0.39 | ND | 0.39 | 0.39 | ND | 0.39 | ND | 1.56 | 0.78 |
| 10 | 0.2 | 0.2 | 0.2 | 0.2 | ND | 0.1 | ND | 0.4 | 0.2 |
| 11 | 0.39 | 1.56 | 0.39 | 0.78 | 0.78 | 0.39 | 0.39 | 0.78 | ND |
a
INH-R, INH-resistant strain; RIF-R, rifampin-resistant strain; TAC-R, thiacetazone-resistant strain; EMB-R, EMB-resistant strain; CIP-R, ciprofloxacin-resistant strain; KAM-R, KAM-resistant strain; ETA-R, ethionamide-resistant strain; PAS-R, p-aminosalicylic acid-resistant strain.
b
ND, not determined.