. 2008 Jul 14;52(9):3339–3349. doi: 10.1128/AAC.00496-08

TABLE 2.

CC₅₀ values derived from scans of gels as exemplified in Fig. 3

Antibiotic	Cleaved-complex CC₅₀ (μM) for enzyme^a:
	Gyrase		Topoisomerase IV
	E. coli	S. aureus	E. coli	S. aureus
Ciprofloxacin	0.2	11	0.6	0.5
Moxifloxacin	0.6	2.5	0.5	0.8
NXL101	>200	>200	0.05	>200

CC₅₀ is the concentration of compound required to inhibit production of linear pBR322 by 50%. Each value is the average of at least two assays.