TABLE 3.
Baseline characteristics of 129 patients with ESBL-producing Escherichia coli bloodstream infections: distribution according to the epidemiological category of the infection
| Patient characteristic | Resulta for patients in the following infection category with the indicated characteristic:
|
|||
|---|---|---|---|---|
| All infections (n = 129) | Nosocomial (n = 109) | Health care associated (n = 18) | Community acquiredb (n = 2) | |
| Demographic information | ||||
| Male sex | 64 (49.6) | 53 (48.6) | 10 (55.5) | 1 |
| Mean age (yr) ± SD | 52 ± 20 | 54 ± 29 | 50 ± 12 | 40 ± 25 |
| Comorbidity | ||||
| Chronic liver disease | 16 (12.4) | 12 (11) | 3 (16.6) | 1 |
| Chronic renal insufficiency | 31 (24) | 27 (24.7) | 3 (16.6) | 1 |
| Diabetes mellitus | 33 (25.6) | 28 (25.6) | 5 (27.7) | 0 |
| Hematological malignancy | 31 (24) | 24 (22) | 6 (33.3) | 1 |
| Solid tumor | 42 (32.5) | 37 (33.9) | 4 (22.2) | 1 |
| Immunosuppression | 48 (37.2) | 42 (38.5) | 6 (33.3) | 0 |
| Prior antimicrobialsc | 73 (56.6) | 59 (54.1) | 12 (66.6) | 2 |
| Prior hospital admissiond | 72 (55.8) | 55 (50.4) | 15 (83.3) | 2 |
| Ward at BSI onset | ||||
| Medicine | 60 (46.5) | 47 (43.1) | 13 (72.2) | 0 |
| Surgery | 62 (48.1) | 56 (51.4) | 4 (22.2) | 2 |
| Intensive care unit | 7 (5.4) | 6 (5.5) | 1 (5.5) | 0 |
| Source of BSI | ||||
| Pancreaticobiliary tract | 32 (24.8) | 26 (23.8) | 6 (33.3) | 0 |
| Central venous catheter | 4 (3.1) | 4 (3.7) | 0 (0) | 0 |
| Lower respiratory tract | 1 (0.7) | 0 (0) | 1 (5.5) | 0 |
| Surgical wound | 17 (13.2) | 16 (14.6) | 1 (5.5) | 0 |
| Urinary tract | 40 (31) | 37 (33.9) | 3 (16.6) | 0 |
| Unknown | 43 (33.3) | 30 (27.5) | 11 (61.1) | 2 |
| Presentation with septic shock | 9 (6.7) | 7 (6.4) | 2 (11.1) | 0 |
| BSI caused by CTX-M-producing isolates | 53 (41.1) | 41 (37.6) | 12 (66.7) | 0 |
| Inadequate initial antimicrobial treatment | 56 (43.4) | 44 (40.4) | 11 (61.1) | 1 |
| 21-day mortality | 38 (29.4) | 29 (26.6) | 8 (44.4) | 1 |
a
Results are numbers (percentages) of patients except where indicated otherwise.
b
The percentage was not calculated when fewer than 10 patients were evaluated.
c
During the 3 months prior to the index blood culture.
d
During the 12 months prior to the index blood culture.