TABLE 5.
Relationship of IQ to change in virus load at week 2a
| Result for IQ of: | Median IQ (range) | Change in log10 virus load from baseline to wk 2
|
|
|---|---|---|---|
| Mean | Median | ||
| <1.0 (n = 7) | 0.76 (0.24-0.89) | −0.6 ± 0.8 | −0.4 (−1.6 to 0.4) |
| ≥1.0 (n = 13) | 1.72 (1.04-29.81) | −1.2 ± 0.8 | −1.4 (−2 to 0.6) |
a
The overall median IQ was 1.3 (range, 0.2-29.8), and the mean IQ was 3.63 ± 7.17. P = 0.24 for the comparison of IQ to virus load change. Based on a median trough of 10.8, a resistance of ≤10-fold achieves an IQ of ≥15. When IQ was calculated using C12h instead of the mean of C0h and C12h, there was no difference in the relationship of IQ and outcome.