FIG. 1.

Kaplan-Meier survival estimates for mice infected by L. monocytogenes according to various schemes of antibiotic administration. BALB/c mice were treated 36 h after intravenous infection by 1 × 10⁵ L. monocytogenes (EGD-e) organisms with a single dose of amoxicillin (50 mg·kg⁻¹ i.p.; n = 12) ○, a single dose of moxifloxacin (50 mg·kg⁻¹ i.p.; n = 12) •, one dose of amoxicillin every 12 h for 5 days (50 mg·kg⁻¹ i.p.; n = 20) ▵, one dose of moxifloxacin every 12 h for 5 days (50 mg·kg⁻¹ i.p.; n = 20) ▴, or sterile isotonic saline (control; n = 5) ▪. The arrows indicate intravenous infection and the start of treatment.