TABLE 1.
Rat | Compound | Recovery (mean % ± SD) for:
|
||
---|---|---|---|---|
Blood | Muscle | Lung | ||
A | LVX | 43.6 ± 5.6 | 38.9 ± 1.7 | 11.4 ± 3.8 |
CIP | 42.9 ± 5.9 | 35.9 ± 1.5 | 11.3 ± 3.8 | |
B | LVX | 48.0 ± 3.0 | 36.8 ± 0.7 | 12.8 ± 3.0 |
CIP | 49.1 ± 3.1 | 36.1 ± 1.8 | 10.9 ± 4.0 | |
C | LVX | 51.0 ± 2.1 | 36.1 ± 3.9 | 6.9 ± 2.4 |
CIP | 56.6 ± 2.0 | 39.1 ± 4.4 | 11.9 ± 2.4 |
CIP and LVX were perfused as a Ringer solution (CIP/LVX mixture at 2 μg·ml−1each) at a flow rate of 0.5 μl·min−1 for 270 min in the blood, muscle, and lung probes of three rats. Values shown are means ± SD for six determinations.