TABLE 2.

Univariate analysis of VR as a function of the presence of mutated or wild-type codons at specific sites of the protease gene

Position	Amino acid	No. of patients	% Responders	P
35	E (wild-type)	56	70	0.0061
	D	72	46
	G	2
	K	2
	N	11
36	M (wild-type)	45	73	0.0037
I	87	47
L	7
V	4
53	F (wild-type)	116	51	0.033
L	23	74
W	1
Y	3
58	Q (wild-type)	119	59	0.072
E	24	38
61	Q (wild-type)	124	58	0.088
D	2	37
E	4
G	1
H	4
N	7
R	1
69	H (wild-type)	120	63	7.22 × 10−5
I	1	17
K	14
N	1
Q	1
R	4
Y	2
89	L (wild-type)	107	61	0.03
I	7	39
M	12
R	1
T	1
V	15