Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reactions with different electrophilic moieties.
| substrate | time | yield | dr | ee of major | ee of minor | ee of 15 | |
|---|---|---|---|---|---|---|---|
| 1 | 13a (n=1) | 1 h | quant. | 2.5:1 | 92% | 87% | 43% |
| 2 | 12b (n=2) | 2 h | quant. | 11:1 | >99% | - | 84% |
| 3 | 13b (n=2) | 16 h | quant. | 11:1 | >99% | - | |
| 4 | 12c (n=3) | 16 h | quant. | 50:1 | >99% | - | 99% |
| 5 | 13c (n=3) | 16 h | 30% | 50:1 | >99% | - |
