TABLE 2.
Any systemic reaction after indicated vaccine (%)* |
|||
---|---|---|---|
Systemic reaction | Age (months) | DTaP-IPV-Hib | DTaP-IPV//Hib† |
Fever (38.0°C or higher) | 2 | 15.1 | 25.7 |
4 | 25.8 | 27.0 | |
6 | 23.5 | 20.2 | |
18 | 32.8 | 32.1 | |
Fussiness | 2 | 56.1 | 54.3 |
4 | 56.8 | 62.9 | |
6 | 48.2 | 45.3 | |
18 | 37.2 | 40.5 | |
Crying | 2 | 39.2 | 40.9 |
4 | 45.3 | 50.2 | |
6 | 30.9 | 35.1 | |
18 | 25.9 | 28.4 | |
Less active | 2 | 49.6 | 52.2 |
4 | 34.2 | 34.3 | |
6 | 17.9 | 22.7 | |
18 | 15.3 | 13.4 | |
Decreased eating | 2 | 37.1 | 36.7 |
4 | 27.9 | 28.3 | |
6 | 23.6 | 25.5 | |
18 | 21.9 | 25.1 | |
Vomiting | 2 | 12.2 | 13.7 |
4 | 9.0 | 8.5 | |
6 | 7.0 | 9.6 | |
18 | 7.6 | 8.7 | |
Diarrhea | 2 | 20.2 | 16.4 |
4 | 10.2 | 12.5 | |
6 | 13.0 | 13.7 | |
18 | 12.3 | 11.0 |
The number of subjects evaluated after doses 1 to 4, respectively, were: diphtheria, tetanus and acellular pertussis, inactivated polio vaccine and Haemophilus influenzae type b (DTaP-IPV-Hib) – 338, 333, 330 and 301, and DTaP-IPV//Hib – 335, 329, 323 and 299;
Data on file (sanofi pasteur, Canada)