Table 3.
Generally applicable SNP profile CCGG1as a diagnostic for CC17. | |||
Calculated against all STs | Sensitivity = 0.91 | Specificity = 0.98 | PPV = 0.90 |
Safety net SNP atr351 "A" allele of as a diagnostic for CC17 – calculated against subsets of STs defined by generally applicable SNPs | |||
CC67 profile STs | Sensitivity = 1 | Specificity = 0.13 | PPV = 0.07 |
CC23 profile STs | Sensitivity = 1 | Specificity = 0.79 | PPV = 0.14 |
CC17 profile STs | Sensitivity = 1 | Specificity = 1 | PPV = 1 |
Safety net SNP "A" allele as a diagnostic for CC17 | |||
Calculated against all STs | Sensitivity = 0.92 | Specificity = 0.82 | PPV = 0.45 |
Safety net SNP "A" allele as a diagnostic for CC17, CC67, CC22 eBURST group | |||
Calculated against all STs | Sensitivity = 0.94 | Specificity = 0.95 | PPV = 0.85 |
1. The generally applicable SNP profile consists of alleles at glnA36, glnA429, glcK180, and adhP111; the safety net SNP is atr351