Table 2.
Sequence homology between P450s 2B1, 2B6, 2B4 and 2B2 for the peptide spanning the amino acid sequence P347 – M376a.
| P450 | Amino acid sequence | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2B1 | 347P | Y | T | D | A | V | I | H | E | I | Q | R | F | S | D | L | V | P | I | G | V | P | H | R | V | T | K | D | T | M376 |
| 2B6 | E | Y | L | M | I | Q | H | S | ||||||||||||||||||||||
| 2B4 | L | G | I | F | T | Q | ||||||||||||||||||||||||
| 2B2 | A | A | L | |||||||||||||||||||||||||||
a
Amino acid sequences were obtained from drnelson.utmem.edu/homepage. Only the residues in P450s 2B6, 2B4, and 2B2 that are different from those in P450 2B1 in this region are shown. The potentially modified serine residue in P450 2B1 at position 360 is indicated in bold.