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. Author manuscript; available in PMC: 2008 Sep 12.
Published in final edited form as: Alcohol Clin Exp Res. 2007 Dec 7;32(1):67–76. doi: 10.1111/j.1530-0277.2007.00554.x

Fig. 2.

Fig. 2

Effects of mGluR antagonists on total locomotor activity alone and in the presence of a sedative dose of ethanol (A, C, and E). Bars represent the mean (±SEM) horizontal distance traveled in 60 minutes (n = 6 to 8) following pretreatment with vehicle, MPEP (30 mg / kg) (A), LY341495 (30 mg / kg) (C), or CPCCOEt (30 mg / kg) (E) with and without ethanol (2.0 g / kg). *Significantly different from vehicle / vehicle (p < 0.05, Tukey’s test). **Significantly different from vehicle / ethanol (p < 0.05, Tukey’s test). Temporal analysis of mean (±SEM) horizontal distance traveled in 5 minute time intervals (n = 6 to 8) following treatment with vehicle, MPEP (30 mg / kg) (B), LY341495 (30 mg / kg) (D), or CPCCOEt (30 mg / kg) (F) with and without ethanol (2.0 g / kg). *mGluR antagonist / ethanol treatment significantly different from vehicle / ethanol treatment at given time point (p < 0.05, Tukey’s test). *mGluR antagonist / vehicle treatment significantly different from vehicle / vehicle at given time point (p < 0.05, Tukey’s test).